What Are the Possible Side Effects of Antipsychotics?
Movement Disorders
Tardive dyskinesia is irreversible, involuntary movement of the face muscles, arms, and legs that results from long-term antipsychotic use. Someone with this condition will uncontrollably pucker their lips and tongue and jerk their arms or legs. Another serious side effect are parkinson-like symptoms of muscle stiffness, tremors, and slow movement.
Neuroleptic Malignant Syndrome
This is a rare but potentially fatal side effect that causes muscle rigidity, fever, high blood pressure, and confusion.
Heart and Circulatory Problems
Long-QT syndrome is a heart rhythm disorder that can be fatal. Antipsychotics may also cause orthostatic hypotension, a drop in blood pressure when you stand or sit up quickly, that can make you fall or faint.
Immune Disruption
Leukopenia or agranulocytosis are side effects that decrease the number of white blood cells in your body, which are necessary to fight infections. This side effect is most often caused by Clozaril.
Other Symptoms
Less serious but common side effects of antipsychotics include:
- Drowsiness
- Dizziness
- Weight gain
- Dry mouth
- Constipation
- Urinary retention
- Elevation in prolactin levels
- Increased risk of diabetes
- Increased cholesterol levels
