Light Pollution May Raise Alzheimer’s Risk — Especially in Young People

In our modern world, the increasing use of bright outdoor artificial light has led to greater productivity, safety, and convenience, but overexposure can disrupt our circadian rhythms and sleep, which can in turn have a negative effect on our physical and mental health.

New research published this week in Frontiers in Neuroscience has found that excessive artificial light at night, or “light pollution,” may contribute to more people developing Alzheimer’s disease, especially adults younger than 65.

“Other studies show that light pollution is associated with numerous disorders and diseases, such as sleep problems, obesity, and even cancer,” says the lead research author Robin Voigt-Zuwala, PhD, an associate professor of medicine and the director of the Circadian Rhythm Research Laboratory at Rush University Medical Center in Chicago. “Our study found that exposure to light at night could be detrimental for brain health as well, particularly for individuals with risk factors for Alzheimer’s disease, such as family history, APOE4+ genotype (the strongest genetic risk factor for Alzheimer’s disease), or comorbid diseases that increase risk like cardiovascular disease.”

Why Younger People May Be More Vulnerable

Using satellite-acquired data, the study authors calculated average nighttime light intensity by state and county (excluding Hawaii and Alaska) between 2012 and 2018. Drawing on Medicare data, they determined Alzheimer’s disease presence in different regions and compared disease prevalence to the level of light intensity in each area. They also incorporated medical data about variables known or believed to be risk factors for Alzheimer’s.

In comparing risk factors, Dr. Voigt-Zuwala and her colleagues found that Alzheimer’s prevalence in people 65 and older was more strongly linked with nightly light pollution than with alcohol abuse, chronic kidney disease, depression, and obesity. Other risk factors, including diabetes, high blood pressure, and stroke, were more strongly connected with Alzheimer’s than light pollution.

For people under 65, however, nighttime light intensity was the No. 1 influence associated with Alzheimer’s. Because no other disease risk factor in this population was as strongly tied to this dementia, scientists suggested that younger people may be particularly sensitive to the effects of light exposure at night.

Voigt-Zuwala notes that younger people tend to have lifestyles that expose them to more light at night.